In 1985, the Medical Practitioner's program was established with the involvement of the University of Guyana, GAHEF, and the Georgetown Public, West Demerara Regional, Davis Memorial and St. Joseph's Mercy Hospitals. 

Then in 1995, the institution was renamed "The School of Medicine, University of Guyana" (UGSM), and its entire curriculum and administrative structure was revised. This paved the way for the development of the Medical School's Pre-clinical and Clinical Departments.

For the first time, in 1996, the School of Medicine, university of Guyana (UGSM) was listed in the WHO World Directory of Medical Schools.

The UG School of Medicine is a national institution established to train Guyanese and international physicians with the capacity to provide the best possible quality of medical care wherever they practice.

A well- recognised medical educational center in the West Indies and South America; committed to excellence in education, research and health services delivery; and the preparation and inspiration of students and faculty for a lifetime of learning service and social commitment to citizens worldwide.

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